Cicada Slough
- Chinese
- 蝉蜕
- Pinyin
- Chan Tui
- Latin
- Periostracum Cicadae
Known in TCM as Chan Tui (蝉蜕), this sweet and salty, slightly cold herb enters the Lung and Liver. Traditionally, it releases wind-heat from the exterior - Chan Tui is used for early wind-heat presentations with sore throat, mild fever, and superficial irritation, most often applied for sore throat, urticaria, and conjunctivitis. Modern research has identified N-acetyldopamine among its active constituents.
Part used: Shed skin
Also Known As
Latin: Periostracum Cicadae | Pinyin: Chan Tui | Chinese: 蝉蜕
TCM Properties
- Taste
- sweet, salty
- Temperature
- slightly cold
- Channels
- Lung, Liver
Traditional Use
Primary Actions
- Releases wind-heat from the exterior - Chan Tui is used for early wind-heat presentations with sore throat, mild fever, and superficial irritation.
- Benefits the throat and voice - it is a classic light herb for hoarseness, swollen throat, and constrained heat at the surface.
- Vents rashes and relieves itching - traditional use includes measles that do not vent well, urticaria, and pruritic wind-type eruptions.
- Extinguishes wind and stops spasms - Chan Tui is also used in combination formulas for fright-wind, childhood convulsion patterns, and tremulous movement associated with wind.
Secondary Actions
- Because it is a cast-off shell rather than a dense tonic substance, Chan Tui is valued for its light, ascending, and outward-venting quality.
- Source processing matters: cleaning and authenticity affect ash burden, heavy-metal content, and overall quality more than many ordinary botanical herbs.
Classic Formulas
- Chan Tui with Niu Bang Zi and Bo He - classic wind-heat throat and rash-venting pairing logic.
- Xiao Feng San - itching formula tradition in which Chan Tui helps vent wind from the skin and reduce pruritus.
- Chan Tui with Jiang Can and Gou Teng - spasm- and convulsion-oriented strategy when wind and agitation rise to the surface.
Classical References
- TCM herb summaries describe Chan Tui as sweet, salty, and slightly cold, entering the Lung and Liver channels, with actions of dispersing wind-heat, venting rashes, benefiting the throat, brightening the eyes, and stopping spasms.
- Traditional use often emphasizes pediatric or dermatologic patterns because the herb's light outward action helps guide constrained pathogens or rash expression to the surface.
- Its classic identity remains distinct from heavier anticonvulsant or sedative substances even though later research has explored neuroprotective effects.
Modern Research
Active Compounds
- N-acetyldopamine dimers and oligomers
- Free amino acids
- Chitinous and protein matrix fractions
- Cyclic peptide constituents
- Trace mineral and heavy-metal burden sensitive to processing quality
Studied Effects
- A 2022 quality and bioactivity study quantified N-acetyldopamine oligomers, amino acids, ash, and heavy metals and found that pre-molting-washed material retained stronger antioxidant and anti-inflammatory activity than standard washed material (PMID 36431784).
- UPLC-QTOF-MS comparison of four origins of Cicadae Periostracum mapped distinct N-acetyldopamine polymer profiles, reinforcing the importance of authenticity and source control in this animal-derived materia medica (PMID 31767224).
- Cicadae Periostracum showed antiepileptic and antiapoptotic effects in mice and PC12 cells through PI3K/Akt/Nrf2-related signaling, offering a mechanistic correlate for the herb's traditional antispasmodic use (PMID 34336105).
- Cicadidae Periostracum attenuated atopic-dermatitis-like inflammation in a mouse model by regulating NLRP3 inflammasome activation, supporting a modern research bridge to its traditional itch-relieving use (PMID 33520088).
PubMed References
- Integrating Multi-Type Component Determination and Anti-Oxidant/-Inflammatory Assay to Evaluate the Impact of Pre-Molting Washing on the Quality and Bioactivity of Cicadae Periostracum (2022)
- Quality consistency evaluation on four origins of Cicadae Periostracum by ultra-performance liquid chromatography coupled with quadrupole/time-of-flight mass spectrometry analysis (2020)
- Antiepileptic Effects of Cicadae Periostracum on Mice and Its Antiapoptotic Effects in H2O2-Stimulated PC12 Cells via Regulation of PI3K/Akt/Nrf2 Signaling Pathways (2021)
- Cicadidae Periostracum Attenuates Atopic Dermatitis Symptoms and Pathology via the Regulation of NLRP3 Inflammasome Activation (2021)
Safety & Interactions
Contraindications
- Rashes or itching that arise from marked deficiency-dryness rather than wind-heat or surface constraint
- Known allergy to insect-derived products
- Use of contaminated or poorly cleaned source material
Cautions
- Most modern evidence is preclinical and does not justify self-treatment of seizures, severe eczema, or acute throat compromise.
- Quality varies with source and processing, and heavy-metal or ash burden is a real practical issue for this insect-derived medicinal material.
- Chan Tui is a light exterior-venting substance, so it is usually less relevant once a rash has already fully expressed or when deep interior pathology predominates.
Conditions
- Sore Throat Traditional ★★★★☆ JSON
- Urticaria Traditional ★★★★☆ JSON
- Conjunctivitis Traditional ★★★☆☆ JSON
- Common Cold Traditional ★★☆☆☆ JSON
- Epilepsy Research ★★☆☆☆ JSON
Frequently Asked Questions
What is Cicada Slough used for?
Cicada Slough is traditionally used to Releases wind-heat from the exterior - Chan Tui is used for early wind-heat presentations with sore throat, mild fever, and superficial irritation., Benefits the throat and voice - it is a classic light herb for hoarseness, swollen throat, and constrained heat at the surface., Vents rashes and relieves itching - traditional use includes measles that do not vent well, urticaria, and pruritic wind-type eruptions., Extinguishes wind and stops spasms - Chan Tui is also used in combination formulas for fright-wind, childhood convulsion patterns, and tremulous movement associated with wind.. Research has investigated its effects on: A 2022 quality and bioactivity study quantified N-acetyldopamine oligomers, amino acids, ash, and heavy metals and found that pre-molting-washed material retained stronger antioxidant and anti-inflammatory activity than standard washed material (PMID 36431784).; UPLC-QTOF-MS comparison of four origins of Cicadae Periostracum mapped distinct N-acetyldopamine polymer profiles, reinforcing the importance of authenticity and source control in this animal-derived materia medica (PMID 31767224)..
What are other names for Cicada Slough?
Cicada Slough is also known as Cicada. In TCM: 蝉蜕 (Chan Tui); Periostracum Cicadae.
Is Cicada Slough safe during pregnancy?
The safety of Cicada Slough during pregnancy has not been established. Consult a qualified healthcare provider before use.
What are the contraindications for Cicada Slough?
Cicada Slough should not be used in: Rashes or itching that arise from marked deficiency-dryness rather than wind-heat or surface constraint; Known allergy to insect-derived products; Use of contaminated or poorly cleaned source material. Consult a qualified practitioner before use.