Flatstem Milkvetch Seed
- Chinese
- 沙苑子
- Pinyin
- Sha Yuan Zi
- Latin
- Semen Astragali Complanati
Known in TCM as Sha Yuan Zi (沙苑子), this sweet, warm herb enters the Kidney and Liver. Traditionally, it tonifies Kidney yang and secures essence - Sha Yuan Zi is a classic deficiency herb for spermatorrhea, urinary frequency, weakness of the lower back, and reproductive leakage patterns, most often applied for impotence, frequent urination, and leucorrhea. Modern research has identified Flavonoid among its active constituents.
Part used: Seed
Also Known As
Latin: Semen Astragali Complanati | Pinyin: Sha Yuan Zi | Chinese: 沙苑子
TCM Properties
- Taste
- sweet
- Temperature
- warm
- Channels
- Kidney, Liver
Traditional Use
Primary Actions
- Tonifies Kidney yang and secures essence - Sha Yuan Zi is a classic deficiency herb for spermatorrhea, urinary frequency, weakness of the lower back, and reproductive leakage patterns.
- Nourishes the Liver and improves vision - traditional use extends to dim vision or blurred sight when Liver-Kidney deficiency rather than acute excess is the root.
- Stabilizes the lower burner gently - compared with harsher astringents, it secures without being excessively drying or mineral-heavy.
Secondary Actions
- Sha Yuan Zi is especially useful when leakage and weakness coexist, because it both supplements and secures rather than simply astringing.
- Its warm, sweet, seed-based nature makes it relatively gentle, so it often appears in long-term deficiency formulas.
Classic Formulas
- Traditional Kidney-deficiency formulas pair Sha Yuan Zi with Tu Si Zi, Fu Pen Zi, or Qian Shi for essence leakage and urinary frequency.
- Vision-support combinations use Sha Yuan Zi with Gou Qi Zi and Ju Hua when deficiency affects the eyes.
- Reproductive-tonic strategies often combine it with Du Zhong, Ba Ji Tian, or Gou Ji when low-back weakness and sexual debility are prominent.
Classical References
- Traditional herbology classifies Sha Yuan Zi as sweet and warm, entering the Kidney and Liver to supplement deficiency, secure essence, and brighten the eyes.
- It is one of the gentler seed tonics used for leakage patterns, especially when stronger hot yang tonics would be too forceful.
- Because it both tonifies and secures, it fits chronic deficiency formulas better than short-term symptomatic strategies.
Modern Research
Active Compounds
- Flavonoid glycosides such as complanatosides - the best-known marker compounds in commercial Sha Yuan Zi quality work
- Saponins and triterpenoid-related constituents - supportive components in broader pharmacologic study
- Phenolic compounds - relevant to antioxidant and metabolic interest
- Seed lipids and minor nitrogenous constituents - part of the seed's tonic profile
Studied Effects
- A 2020 paper profiled bioactive flavonoid glycosides in commercial Astragali Complanati Semen, improving the chemical basis for modern Sha Yuan Zi standardization (PMID 33081333).
- Metabolomics-based research reported a hypocholesterolemic effect from Astragali Complanati Semen, suggesting broader cardiometabolic relevance beyond its classical reproductive use (PMID 28753987).
- Semen Astragali Complanati enhanced bone formation in osteoporotic rats, which provides a modern experimental bridge to the herb's traditional role in weakness and deficiency of the low back and bones (PMID 23782721).
- A total flavonoid fraction from Astragalus complanatus showed antihypertensive activity in rats, though this remains preclinical evidence rather than direct clinical confirmation (PMID 16201455).
PubMed References
- Bioactive Flavonoid Glycosides and HPLC and UPLC Quantification of Commercial Astragali Complanati Semen (2020)
- Chemical Analysis of Astragali Complanati Semen and Its Hypocholesterolemic Effect Using Serum Metabolomics Based on Gas Chromatography-Mass Spectrometry (2017)
- Semen Astragali Complanati- and Rhizoma Cibotii-enhanced bone formation in osteoporosis rats (2013)
- Antihypertensive effect of total flavonoid fraction of Astragalus complanatus in hypertensive rats (2005)
Safety & Interactions
Contraindications
- Damp-heat or excess conditions causing urinary symptoms rather than deficiency leakage
- Fire from yin deficiency without true Kidney-yang weakness
Cautions
- Sha Yuan Zi is generally mild, but it is not the right choice for acute infection or inflammatory urinary complaints driven by damp-heat.
- Concentrated extracts studied in modern research are not necessarily equivalent to classical seed decoctions.
- MSK page not found - drug interaction data not available from Memorial Sloan Kettering integrative medicine database
Drug Interactions
- Antihypertensive medications - theoretical additive effect based on preclinical flavonoid research
Conditions
- Impotence Traditional ★★★☆☆ JSON
- Frequent Urination Traditional ★★★☆☆ JSON
- Leucorrhea Traditional ★★★☆☆ JSON
- Blurred Vision Traditional ★★★☆☆ JSON
Frequently Asked Questions
What is Flatstem Milkvetch Seed used for?
Flatstem Milkvetch Seed is traditionally used to Tonifies Kidney yang and secures essence - Sha Yuan Zi is a classic deficiency herb for spermatorrhea, urinary frequency, weakness of the lower back, and reproductive leakage patterns., Nourishes the Liver and improves vision - traditional use extends to dim vision or blurred sight when Liver-Kidney deficiency rather than acute excess is the root., Stabilizes the lower burner gently - compared with harsher astringents, it secures without being excessively drying or mineral-heavy.. Research has investigated its effects on: A 2020 paper profiled bioactive flavonoid glycosides in commercial Astragali Complanati Semen, improving the chemical basis for modern Sha Yuan Zi standardization (PMID 33081333).; Metabolomics-based research reported a hypocholesterolemic effect from Astragali Complanati Semen, suggesting broader cardiometabolic relevance beyond its classical reproductive use (PMID 28753987)..
What are other names for Flatstem Milkvetch Seed?
Flatstem Milkvetch Seed is also known as Astragali. In TCM: 沙苑子 (Sha Yuan Zi); Semen Astragali Complanati.
Is Flatstem Milkvetch Seed safe during pregnancy?
The safety of Flatstem Milkvetch Seed during pregnancy has not been established. Consult a qualified healthcare provider before use.
What are the contraindications for Flatstem Milkvetch Seed?
Flatstem Milkvetch Seed should not be used in: Damp-heat or excess conditions causing urinary symptoms rather than deficiency leakage; Fire from yin deficiency without true Kidney-yang weakness. Consult a qualified practitioner before use.
Does Flatstem Milkvetch Seed interact with any medications?
Flatstem Milkvetch Seed may interact with: Antihypertensive medications - theoretical additive effect based on preclinical flavonoid research. Always inform your healthcare provider of any herbal supplements you are taking.