Hemp Seed
- Chinese
- 麻子仁
- Pinyin
- Ma Zi Ren
- Latin
- Fructus Cannabis
Known in TCM as Ma Zi Ren (麻子仁), this sweet, neutral herb enters the Spleen, Stomach, and Large Intestine. Traditionally, it moistens dryness and relieves constipation - Ma Zi Ren is the classic formula-facing name for hemp seed in bowel-dryness patterns, especially the 'Pi Yue' constipation tradition, most often applied for constipation. Modern research has identified Fixed among its active constituents.
Part used: Fruit
Also Known As
Latin: Fructus Cannabis | Pinyin: Ma Zi Ren | Chinese: 麻子仁
TCM Properties
- Taste
- sweet
- Temperature
- neutral
- Channels
- Spleen, Stomach, Large Intestine
Traditional Use
Primary Actions
- Moistens dryness and relieves constipation - Ma Zi Ren is the classic formula-facing name for hemp seed in bowel-dryness patterns, especially the 'Pi Yue' constipation tradition.
- Softens stool without harsh purging - it is chosen when the treatment strategy needs lubrication plus gentle movement rather than drastic draining.
- Supports deficiency-pattern constipation - classical use particularly fits patients who are dry, depleted, postpartum, or elderly rather than robust excess cases.
Secondary Actions
- This record preserves the formula-facing Ma Zi Ren identity rather than duplicating the broader Huo Ma Ren food-medicine entry word for word.
- In practice the two names often overlap, but Ma Zi Ren most strongly evokes the classical bowel formula tradition anchored by Ma Zi Ren Wan.
Classic Formulas
- Ma Zi Ren Wan - the canonical Shang Han Lun formula for Pi Yue constipation built around hemp seed lubrication, Bai Shao nourishment, and mild downward movement.
- Run Chang Wan-style moistening combinations - later traditions using Ma Zi Ren when dryness, weak fluids, and difficult stool coexist.
- Post-illness and postpartum bowel formulas - hemp seed paired with qi-supportive or blood-restoring herbs so that bowel movement is restored without injury to the patient.
Classical References
- Classical formula teaching preserves Ma Zi Ren as the signature moistening seed for dry-bound constipation, especially in the Ma Zi Ren Wan lineage.
- The same official modern Chinese herb references that describe Huo Ma Ren also reinforce the seed's role in elderly, postpartum, and deficiency-dryness constipation.
Modern Research
Active Compounds
- Fixed oils rich in linoleic and alpha-linolenic acid - the physiologic basis for the seed's lubricating reputation
- Fiber and protein fractions - supportive nutritional components in broader hemp-seed research
- Minor phenolic and flavonoid compounds - background antioxidant constituents
Studied Effects
- A 2013 randomized controlled trial reported benefit from Ma Zi Ren Wan in functional constipation, offering one of the clearer modern clinical bridges between classical bowel-dryness formula logic and contemporary outcomes (PMID 24473591).
- A larger 2018 randomized trial again found MaZiRenWan effective in patients with functional constipation, strengthening the formula-level evidence linked to this seed's traditional identity (PMID 29654915).
- Broader hemp-seed review literature continues to support the seed's nutrient and lipid richness, but that evidence is best seen as context rather than as direct proof of the classical TCM indication (PMID 40699152).
PubMed References
- Chinese herbal medicine for functional constipation: a randomised controlled trial. (2013)
- Efficacy of MaZiRenWan, a Chinese Herbal Medicine, in Patients With Functional Constipation in a Randomized Controlled Trial. (2018)
- Hemp seed as an emerging source of nutritious functional ingredients. (2026)
Safety & Interactions
Contraindications
- Loose stool or chronic diarrhea
- Cold-slippery bowel patterns without dryness
Cautions
- Ma Zi Ren formulas are meant for dryness-associated constipation and are a poor fit for patients whose bowel looseness already reflects deficiency or dampness.
- Chinese reference sources caution against combined use with anticholinergic drugs such as atropine.
- Even though the seed comes from Cannabis sativa, classical Ma Zi Ren use should not be confused with psychoactive cannabis preparations.
Drug Interactions
- Anticholinergic drugs such as atropine - official Chinese reference sources list this combination as inappropriate.
Conditions
- Constipation Clinical ★★★★☆ JSON
Frequently Asked Questions
What is Hemp Seed used for?
Hemp Seed is traditionally used to Moistens dryness and relieves constipation - Ma Zi Ren is the classic formula-facing name for hemp seed in bowel-dryness patterns, especially the 'Pi Yue' constipation tradition., Softens stool without harsh purging - it is chosen when the treatment strategy needs lubrication plus gentle movement rather than drastic draining., Supports deficiency-pattern constipation - classical use particularly fits patients who are dry, depleted, postpartum, or elderly rather than robust excess cases.. Research has investigated its effects on: A 2013 randomized controlled trial reported benefit from Ma Zi Ren Wan in functional constipation, offering one of the clearer modern clinical bridges between classical bowel-dryness formula logic and contemporary outcomes (PMID 24473591).; A larger 2018 randomized trial again found MaZiRenWan effective in patients with functional constipation, strengthening the formula-level evidence linked to this seed's traditional identity (PMID 29654915)..
What are other names for Hemp Seed?
Hemp Seed is also known as Ma Ren, Hemp Seed Kernel. In TCM: 麻子仁 (Ma Zi Ren); Fructus Cannabis.
Is Hemp Seed safe during pregnancy?
The safety of Hemp Seed during pregnancy has not been established. Consult a qualified healthcare provider before use.
What are the contraindications for Hemp Seed?
Hemp Seed should not be used in: Loose stool or chronic diarrhea; Cold-slippery bowel patterns without dryness. Consult a qualified practitioner before use.
Does Hemp Seed interact with any medications?
Hemp Seed may interact with: Anticholinergic drugs such as atropine - official Chinese reference sources list this combination as inappropriate.. Always inform your healthcare provider of any herbal supplements you are taking.